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Zero-hallucination LLM · ACMG-aware · HIPAA-conscious

Your genetic report,
in plain English.

Upload a WGS, WES, clinical CSV, InterVar TXT, or microbiome report. Ask anything in lay language — Genelio's clinical-grade AI answers grounded in your actual data, with every variant traceable to the row it came from.

76,000
variants per report
< 1.3s
to parse + index
8
report types
genelio.com · InterVar TXT · MG-100
Do I have any likely pathogenic variants?
Your report contains 6 likely pathogenic variants. Top three by CADD:
ACTN3
Likely pathogenic
chr11:66560624 C>T · NM_001104:exon15:c.C1729T:p.R577X
ANO5
Likely pathogenic
chr11:22221100 · NM_001142649:exon5:c.182dupA:p.N63Kfs*15
🔒 Anchored on rows 1,247 + 992 of your report.
Trillions
Data points analyzed
6+
Integrated data layers
98%
Molecular intelligence
0
Hallucinated variants
One base · three ways in

Choose your experience

The same grounded knowledge base, in the language that fits you. The science underneath never changes — only how it's explained.

For you
Plain English

Clear answers about your health. No jargon, nothing scary.

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For clinicians
Clinical

ClinVar & ACMG verbatim, structured for the visit.

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For the lab
Technical

Full-fidelity variant data — query, filter, export.

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How it works

From upload to insight in three steps.

No special training required. Genelio handles the parsing, the indexing, and the safety checks — you just have a conversation.

01

Upload your report

Drop in a PDF, CSV, or TXT from BioAro, Genoox, ANNOVAR, InterVar, or any major lab. We parse it on our servers — never shared.

02

Ask in plain English

“Do I have any BRCA1 variants?” · “I have hearing loss, anything related?” · “What does CADD_phred mean?” Symptom-to-HPO mapping built in.

03

Answers traceable to the row

Every variant carries its source row, every count is real, every classification is quoted verbatim from your report. No hallucinations.

Example conversations

Real questions, grounded answers.

QDo I have any BRCA1 variants?
Your report contains 0 variants in BRCA1. Complete scan across all 3,252 annotated rows.
biofilterdeterministic
QI have severe muscle weakness. Any related variants?
9 variants intersect genes associated with muscle weakness (HP:0001324), including ANO5 (Likely pathogenic, Miyoshi MD), ATXN3 (Machado-Joseph disease), and STIM1 (Stormorken syndrome).
HPO9 matches
QHow many variants have PVS1 = 1?
52 variants with PVS1 = 1. PVS1 is a Very Strong ACMG criterion — null variant in a LOF-known gene.
ACMGaggregate
QWhat does CADD_phred mean?
Phred-scaled pathogenicity score. ≥10 mildly deleterious · ≥15 moderately · 20–30 likely deleterious · >30 top 0.1% of variants.
schema

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