clinical
For clinicians

Clinical-grade variant interpretation.

ClinVar and ACMG evidence surfaced verbatim, structured for the visit. Peer-to-peer, never paraphrased into something softer or stronger.

Compare experiences

Variants scanned

76,330

Pathogenic

7

VUS

198

SERPINA1 · rs17580 · p.E288VClinVar Pathogenic
Built for the visit

Evidence you can act on

Everything a clinician needs to read a report fast — nothing invented.

ClinVar & InterVar verbatim

Classifications quoted exactly — Conflicting stays Conflicting, never paraphrased into something softer or stronger.

Curator vs. algorithm

ClinVar takes precedence over InterVar; algorithm-only flags are surfaced separately and labelled lower-confidence.

HPO symptom mapping

Enter a presenting symptom; we map it to HPO terms and show which of the patient's variants intersect.

ACMG evidence, explicit

PVS1, PM, BA1 and the rest spelled out per variant — the same rule set your lab applies.

In practice

Questions you'd actually ask

Returns ClinVar-Pathogenic / Likely-pathogenic variants first (human-curated, actionable), each with HGVS, zygosity and associated condition — then InterVar-only flags noted separately as lower confidence.
Standards

Faithful to the source

Genelio is a literacy and triage tool — it informs the clinician, it doesn't decide.

Defers appropriately

Treatment questions route to the physician; reproductive risk to a genetic counselor. Never a prescription.

Validated, not vibes

A deterministic post-check strips any variant or classification the model can't match to the report.

Read the report in minutes

Open the console and query the patient's variants directly.